Basic Info.
Certification
GMP, Hse, ISO 9001, USP, Bp
Suitable for
Poultry, Pets
Grade Standard
Pharmaceutical Grade
Shelf Life
2 Years Proper Storage
Application
Nootropics Powder
Transport Package
Standard Packaging or Customized to Your Needs
Specification
1KG 5KG 25KG 50KG
Product Description
1.Free Samples.
2.MOQ:10kg.
3.More than 3000 kinds of animal drugs.
4.More than 11+ manufacturing experience.
5.Certification:MSDS,HALAL,COA,IFRA,ISO9001, ISO22000,26 Allergens, etc.
6.Lead time:about 8-12 working days.
8.Verified by Made-in-China as Golden Supplier. What is Acetyl Hexapeptide-1raw Peptide Powder ?HBT1
HBT1 is an AMPA receptor enhancer that induces the production of brain-derived neurotrophic factor (BDNF) and has little or no excitatory effect in primary neurons. HBT1 binds to the ligand binding domain of AMPA-R in a glutamate-dependent manner.
HBT1 bound to the ligand-binding domain (LBD) of AMPA-R in a glutamate-dependent manner.?The mode of HBT1 and LY451395 binding to a pocket in the LBD of AMPA-R differed: HBT1, formed hydrogen bonds with S518 in the LBD.?Lower agonistic profile of HBT1 may associate with its lower risks of bell-shaped responses in BDNF production in primary neurons.
Product name: YDL223C |
Other Name: HBT1 |
Appearance:Yellowish Powder |
CAS:489408-02-8 |
M.F.:C16H17F3N4O2S |
M.W.:386.39 |
Specification:99% |
HBT1 Powder Base Information
Name: HBT1 powder
CAS: 489408-02-8
Purity: 98%
Chemical name: 2-(((5-Methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)acetyl)amino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
Synonyms: HBT1; HBT-1; HBT 1
Molecular Formula: C16H17F3N4O2S
Molecular Weight: 386.39
Melting Point: /
Form: powder
Appearance: white to beige
Solubility: DMSO: 2 mg/mL, clear
Storage Condition: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
Application: AMPA receptor potentiator
Benefits of HBT1
AMPA-R agonists, which can activate all AMPA-Rs, including resting receptors, have been shown to induce both desensitization of AMPA-R and seizure (Yamada, 1998; Beattie et al., 2000; Ehlers, 2000). AMPA-R potentiators are considered to have better pharmacological profiles because of their selective enhancement of physiologic activation of AMPA-Rs in the brain. However, AMPA-R potentiators such as LY451646, LY451395, and S18986 are reported to elicit bell-shaped responses in various pharmacological effects: LY451646 is reported to show bell-shaped responses in in vivo BDNF induction, and the bell-shaped response of LY451395 in the radial maze task was described in the introduction section of a report about LY451395 (Mackowiak et al., 2002; Bai et al., 2003; Fowler et al., 2004; Jhee et al., 2006; Bernard et al., 2010). PF-4778574 is reported to have less than a 30-fold safety margin against seizure in rodents (Shaffer et al., 2013). Thus, discovery of AMPA-R potentiators with lower risks of these issues is needed.
ShangHai Twochem is one of professional groups specialized in research, development, custom manufacturing and trading of pharmaceutical API, advanced intermediates, food supplements, hookah additive flavors ,Cosmetic raw materials, health and cosmetic raw materials, polypeptides, animal drug and organic reagent etc. You can select more than 2000 kinds of raw ingredients here. And we are keeping developing new products and continuously marketing them for sale. You will save lots of time , energy, money and have a very pleasant cooperation with us! We have cooperated with local Medicine Inspection Center as our QC center. We have customer manufacture sites managed under GMP guidline in Anhui and Jiangsu Province, China. We have good relationship with many pharmaceutical research Institute and Universities in China.
Q&A
1.How could l get a sample?
Before we received the first order, please afford the sample cost and express fee. We wilreturn the sample cost back to you within your first order.
2.Can you make designs for us?
We have a professional design team to help our customers do design work.Both OEM and ODM orders are accepted.
3.Can we get samples from your factory?
We can provide you samples for free, you just pay express cost.
4.Whether you could make our brand on your products?
Yes. We can print your Logo on both the products and the packages if you can meet our MOQ
How can you provide us high quality products?
5.We have a professional QC team, every product is shipped after strictly examination.
What is your lead time?
Quantity about 10000 pcs is 15-20 days ,small orders are about one week.
Huge orders to be neqotiated.
6.What is your payment?
We accept T/T.L/C.Westem union or to be negotiated.Don't worry about anything, if you have any problems, please feel free to contact us
Address:
N/a, Shanghai, China
Business Type:
Trading Company
Business Range:
Chemicals
Management System Certification:
ISO 9001, OHSAS/ OHSMS 18001, HSE, ISO 14064, QC 080000, GMP, BSCI, IFS, PAS 28000
Company Introduction:
Shanghai Twochem is one of professional groups specialized in research, development, custom manufacturing and trading of pharmaceutical API, advanced intermediates, food supplements/Cosmetic raw materials, health and cosmetic rawmaterials, herbal extracts, polypeptides and prostaglandin derivatives etc.