| Customization: | Available |
|---|---|
| CAS No.: | 93479-97-1 |
| Formula: | C24h34n4o5s |
Suppliers with verified business licenses
Audited Supplier Audited by an independent third-party inspection agency
1.Free Samples.
| Product Name | Glimepiride |
| CAS No. | 93479-97-1 |
| MF | C24H34N4O5S |
| MW | 490.61556 |
| Appearance and shape | White fine Powder |
Glimepiride is a third-generation sulfonylureas long-acting anti-diabetes drug. The main mechanism of its hypoglycemic effect is to stimulate the secretion of by beta cells of the pancreas and partially increase the sensitivity of surrounding tissues. This product binds to receptor and dissociates faster than glyburide, and causes less severe hypoglycemia. Its mechanism is through and sulfonyl urea receptors on the surface of the pancreatic beta cells (relative molecular mass of 6.5 x 104 protein), the receptor and ATP sensitive K + (KATP) channel phase coupling, pushing the KATP channel close, cause cell membrane depolarization, makes the open voltage dependent calcium channel, Ga2 + internal flow and lead to the release, and inhibit the synthesis of liver glucose. Recent studies have shown that different sulfonylurea coal drugs have different affinities with KATP. The following order: Glenn beauty urea > tolbutamide > sulfonyl chloride propyl urea. In addition, it could be a glucose transporter factor 1, 4 caused by two kinds of protein expression is increased. Due to Glenn beauty of urea to cardiovascular KATP channels in the weaker than Glenn wave urea, gliclazide pass column pyrazine. So cardiovascular adverse reactions are also rare.
Q&A
1.How could l get a sample?
Before we received the first order, please afford the sample cost and express fee. We wilreturn the sample cost back to you within your first order.
2.Can you make designs for us?
We have a professional design team to help our customers do design work.Both OEM and ODM orders are accepted.
3.Can we get samples from your factory?
We can provide you samples for free, you just pay express cost.
4.Whether you could make our brand on your products?
Yes. We can print your Logo on both the products and the packages if you can meet our MOQ
How can you provide us high quality products?
5.We have a professional QC team, every product is shipped after strictly examination.
What is your lead time?
Quantity about 10000 pcs is 15-20 days ,small orders are about one week.
Huge orders to be neqotiated.
6.What is your payment?
We accept T/T.L/C.Westem union or to be negotiated.Don't worry about anything, if you have any problems, please feel free to contact us
){kind=link}