Customization: | Available |
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CAS No.: | 551-11-1 |
Formula: | C20h34o5 |
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Product name | Dinoprost |
Cas number | 551-11-1 |
Molecular formula | C20H34O5 |
Molecular weight | 354.48 |
Appearance | White to off-white crystalline solid |
Melting point | 25-35ºC |
Boiling point | 531ºC at 760 mmHg |
Relative density | 1.153 g/cm3 |
Indications
Induced abortion in the second trimester of pregnancy (16 weeks to 20 weeks) and expired abortion, fetal death or congenital malformation of the fetus can also be used for induction of labor during term pregnancy and for angiography.
Pharmacokinetics
Absorption after amniocentesis, slowly entering the systemic circulation, the average abortion takes 20h ~ 24h, T1/2 in amniotic fluid is 3h ~ 6h, T1/2 is shorter than 1min in intravenous injection. Degraded in the lungs and liver, metabolites are mainly excreted from the kidneys.
Product name | Dinoprost |
CAS | 38562-01-5 |
Appearance | white powder |
Assay | 99% |
Storage | Cool and Protect from light |
Prostaglandin F2α (PGF2α in the name of prostaglandin), pharmacologically known as denoprost (INN), is used in medicine as a natural prostaglandin for labor induction and abortion.In mammals, it is produced when the uterus is stimulated, and because no fertilized eggs are present during the follicular phase, the uterus produces PGF2A.It acts on the corpus luteum and causes the degeneration of the corpus luteum, forming the fibrotic white body of the ovary.The activation of PGF2α is based on the number of luteal mode receptor 0.The PGF2α subtype 8-isoprostaglandin F2α was found to be significantly increased in patients with endometriosis and is therefore a potential factor for oxidative stress associated with endometriosis.
1. Mid-gestation induced abortion (16 ~ 20 weeks), also applicable to expired abortion, fetal death in utero or more obvious fetal congenital malformations induced labor.
2. Intravenous infusion of low-concentration liquid medicine can be used to induce labor during full-term pregnancy;
3. Intravenous injection can be used as a vasodilator for angiography.
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Quantity about 10000 pcs is 15-20 days ,small orders are about one week.
Huge orders to be neqotiated.
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