Customization: | Available |
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CAS No.: | 872365-14-5 |
Formula: | C19h17f3n2o4s |
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Chemical name
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Fevipiprant |
CAS No.
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872365-14-5 |
MF:
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C24H19FN2O3
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MW:
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402.4176632
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Purity
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98%min
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Certificate
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ISO 9001
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Storage Temperature
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Cool Dry Place
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Fevipiprant, a drug primarily used to treat asthma, has recently been explored for its potential use in hair care. There is evidence to suggest a link between hair loss and inflammation in the scalp, and fevipiprant's anti-inflammatory properties could provide benefits for those experiencing hair loss or thinning.
Studies have shown that fevipiprant can reduce levels of certain inflammatory molecules in the scalp which contribute to hair loss. This suggests that fevipiprant could potentially be used as a preventative treatment for hair loss, particularly in individuals with underlying inflammatory scalp conditions.
Furthermore, fevipiprant may also promote hair growth. A study conducted on mice showed that treatment with fevipiprant increased hair growth and thickness compared to a control group. While more research is needed to determine its effectiveness in humans, these preliminary findings suggest that fevipiprant could have a positive impact on hair growth.
Function of Fevipiprant CAS 872365-14-5
Fevipiprant, also known as NVP-QAW039 or QAW039, is an oral active and potent CRTh2 receptor antagonist and potentially useful for asthma treatment. [(3)H]-QAW039 displayed high affinity for the human CRTh2 receptor (1.14 ± 0.44 nM) expressed in Chinese hamster ovary cells, the binding being reversible and competitive with the native agonist prostaglandin D2(PGD2). QAW039 was also a potent inhibitor of PGD2-induced cytokine release in human Th2 cells. Fevipiprant reduces eosinophilic airway inflammation and is well tolerated in patients with persistent moderate-to-severe asthma and raised sputum eosinophil counts despite inhaled corticosteroid treatment. Fevipiprant demonstrates a favorable safety profile.
Fevipiprant is the drug for the treatment of hair loss dwindled, perhaps due more to commercial potential and chemical stability reasons than efficacy as the later studies of Setipiprant have focused on different chemical forms of the drug and combining it with various nanoparticles to enhance delivery.
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