Customization: | Available |
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CAS No.: | 73-78-9 |
Formula: | C14h23cln2o |
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Lido caine hydrochloride is metabolized rapidly by the liver, and metabolites and unchanged drug are excreted by the kidneys. Biotransformation includes oxidative N-dealkylation, ring hydroxylation, cleavage of the amide linkage, and conjugation. N-dealkylation, a major pathway of biotransformation, yields the metabolites monoethylglycinexylidide and glycinexylidide. The pharmacological/toxicological actions of these metabolites are similar to, but less potent than, those of Lidoca ine hydrochloride. Approximately 90% of Lidoca ine hydrochloride administered is excreted in the form of various metabolites, and less than 10% is excreted unchanged. The primary metabolite in urine is a conjugate of 4-hydroxy-2,6-dimethylaniline.
1. Lidoc aine, xylocaine, or lignocaine is a common local anesthetic and class-1b antiarrhythmic drug. Lid ocaine is used topically to relieve itching, burning, and pain from skin inflammations, injected as a dental anesthetic, or as a local anesthetic for minor surgery.
2.It is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basic healthcare system.
3. Lidoc aine is the most important class-1b antiarrhythmic drug; it is used intravenously for the treatment of ventricular arrhythmias if amiodarone is not available or contraindicated.
4. Lid ocaine should be given for this indication after defibrillation, CPR, and vasopressors have been initiated. A routine prophylactic administration is no longer recommended for acute cardiac infarction; the overall benefit of this measure is not convincing.
Product Name | Factory Supply Pharmaceutical Chemical Li docaine Hcl Hydrochloride Powder CAS 73-78-9 Lido caine |
Appearance | white powder |
CAS | 73-78-9 |
Assay | 99% |
Keywords | Lidocai ne Hcl Hydrochloride;Lido caine HCl;Lidoc aine Hydrochloride Powder |
Shelf Life | 24 months when properly stored |
Storage | Keep in a cool, dry, dark location |
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