1.Free Samples.
2.MOQ:500g.
3.More than 3000 kinds of animal drugs.
4.More than 11+ manufacturing experience.
5.Certification:MSDS,HALAL,COA,IFRA,ISO9001, ISO22000,26 Allergens, etc.
6.Lead time:about 8-12 working days.
8.Verified by Made-in-China as Golden Supplier.
What is Felodipine Powder CAS 72509-76-3?
Product Information |
Other Name |
Felodipine |
Assay |
99% |
Apprearance |
White to light yellow crystallline powder |
Package |
1kg/carton; 25kg/drum |
Payment |
Alipay; Western Union; TT |
Shipment |
DHL; FedEx, EMS; Air; Sea |
Standard |
USP/EP/CP/BP |
Storage |
Sealed in dark and dry place |
Shelf Life |
2 Years |
Felodipine is used for the treatment of hypertension. It is a selective calcium antagonist, mainly inhibits the inward flow of extracellular calcium in the smooth muscle of small arteries, selectively dilates small arteries, has no effect on veins, and does not cause postural hypotension. The product does not affect glomerular filtration rate and creatinine clearance rate while decreasing renal vascular resistance, and renal blood flow is unchanged or even slightly increased, with pro-sodium excretion and diuretic effect. It increases output and cardiac index, significantly reduces afterload, and has no significant effect on cardiac systolic function, preload and heart rate.
Function of Felodipine Powder CAS 72509-76-3
Felodipine is a vasodilatory calcium antagonist with a high degree of vascular selectivity. It is currently indicated for use only in hypertension, either as monotherapy or in conjunction with diuretics or beta blockers
Felodipine is a 1,4-dihydropyridine small molecule antagonist and calcium channel protein inhibitor. Antagonism of the vascular L-type (long-lasting) calcium channel decreases intracellular calcium concentration, softening the tone of vascular tissue and decreasing the peripheral resistance upon the blood stream, effectively decreasing systemic arterial blood pressure without affecting myocardial contractility. Felodipine is described to inhibit cytokine-induced NO and superoxide production as well as cytokine-induced NO synthase (NOS) mRNA induction, and is suggested to act as a scavenger of superoxide and not an inhibitor of inducible NOS induction. This indicates that Felodipine further protects the vasculature against endogenous free radical generation during inflammatory responses.
It is used for the treatment of hypertension, cardiac colic, congestive heart failure, and is effective for all degrees of hypertension.
Also used for the treatment of high blood pressure is a selective calcium antagonists, inhibit the main flow of extracellular calcium arterial smooth muscle cells, and selective expansion of small arteries, veins, no such effect, not cause orthostatic hypotension; myocardial also. no significant inhibition. This product reduces renal vascular resistance, while not affect glomerular filtration rate and creatinine clearance rate, renal blood flow did not change even slightly increased, there natriuretic and diuretic effect. It can be used to increase output and cardiac index, significantly reducing afterload, while the systolic function, preload and heart rate had no significant effect.
Specification
ShangHai Twochem is one of professional groups specialized in research, development, custom manufacturing and trading of pharmaceutical API, advanced intermediates, food supplements, hookah additive flavors ,Cosmetic raw materials, health and cosmetic raw materials, polypeptides, animal drug and organic reagent etc. You can select more than 2000 kinds of raw ingredients here. And we are keeping developing new products and continuously marketing them for sale. You will save lots of time , energy, money and have a very pleasant cooperation with us! We have cooperated with local Medicine Inspection Center as our QC center. We have customer manufacture sites managed under GMP guidline in Anhui and Jiangsu Province, China. We have good relationship with many pharmaceutical research Institute and Universities in China.
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Q&A
1.How could l get a sample?
Before we received the first order, please afford the sample cost and express fee. We wilreturn the sample cost back to you within your first order.
2.Can you make designs for us?
We have a professional design team to help our customers do design work.Both OEM and ODM orders are accepted.
3.Can we get samples from your factory?
We can provide you samples for free, you just pay express cost.
4.Whether you could make our brand on your products?
Yes. We can print your Logo on both the products and the packages if you can meet our MOQ
How can you provide us high quality products?
5.We have a professional QC team, every product is shipped after strictly examination.
What is your lead time?
Quantity about 10000 pcs is 15-20 days ,small orders are about one week.
Huge orders to be neqotiated.
6.What is your payment?
We accept T/T.L/C.Westem union or to be negotiated.Don't worry about anything, if you have any problems, please feel free to contact us