1.Free Samples.
2.MOQ:500g.
3.More than 3000 kinds of animal drugs.
4.More than 11+ manufacturing experience.
5.Certification:MSDS,HALAL,COA,IFRA,ISO9001, ISO22000,26 Allergens, etc.
6.Lead time:about 8-12 working days.
8.Verified by Made-in-China as Golden Supplier.
What is 6-Methoxynicotinamide Powder CAS 7150-23-4 ?
English name: Jbsnf-000088
CAS number: 7150-23-4
Molecular formula: C7H8N2O2
Molecular weight: 152.15
Melting point 23-25 °C
Boiling point 128-130 °C (14 mmHg)
Density 1.00 g/mL at 20 °C
Refractive index n20/D 1.479(lit.)
Flash point >230°F
Storage conditions 2-8°C
Solubility H2O: 1 M at 20 °C, clear, colorless
Form: Liquid After Melting
Acidity coefficient (pKa):10.53±0.19 (Predicted)
Specific gravity: 0.925
PH value: 12.0-13.5 (25ºC, 1M in H2O)
Water solubility: Miscible with water, ethanol and ether.
Place of Origin: China Yinherb-Lab
Packing: As per client's requirements
Minimum Order Quantity: 1kg
Storage: Store in cool & dry place, Keep away from strong light and heat for 2 years
Function of JBSNF-000088
JBSNF-000088 is an inhibitor of nicotinamide N-methyltransferase (NNMT; IC50s = 1.8, 2.8, and 5 µM for human, monkey, and mouse NNMT, respectively).1 It inhibits NNMT and reduces 1-methyl-nicotinamide (MNA) levels in U2OS and 3T3L1 cells (IC50s = 1.6 and 6.3 µM, respectively).
JBSNF-000088 (50 mg/kg) reduces visceral white adipose tissue (WAT) MNA levels, body weight, fed blood glucose levels, and plasma and liver triglyceride levels, and improves oral glucose tolerance in a mouse model of diet-induced obesity (DIO).
It also improves glucose tolerance, without affecting body weight, in the ob/ob and db/db mouse models of in sulin resistance and diabetes, respectivel
Each of these peptides has a positive impact of energy metabolism. NMN, for instance, boosts NAD levels. Low NAD has long been associated with obesity while high NAD is generally associated with healthy diets rich in vegetables. High levels of NAD are associated with ideal body mass composition and increased longevity. High NAD levels will definitely increase energy metabolism and lower obesity.
All three of these compounds can help to reduce the risk of diabetes. JBSNF-000088 is the most potent anti-diabetic in this group and has been shown in mouse models to drastically improve glucose handling, even in genetically obese mice.
Like JBSNF-000088, 5 amino-1MQ helps to regulate blood sugar levels by decreasing activity of NNMT. In this case, the research indicates that 5-amino-1MQ increases the transport of glucose by boosting GLUT-4 expression.
NAD is a primary marker of aging, declining over time and in certain disease conditions. NMN enhances NAD biosynthesis. In mouse models, NMN administration has been shown to mitigate age-related physiological decline without any side effects.
ShangHai Twochem is one of professional groups specialized in research, development, custom manufacturing and trading of pharmaceutical API, advanced intermediates, food supplements, hookah additive flavors ,Cosmetic raw materials, health and cosmetic raw materials, polypeptides, animal drug and organic reagent etc. You can select more than 2000 kinds of raw ingredients here. And we are keeping developing new products and continuously marketing them for sale. You will save lots of time , energy, money and have a very pleasant cooperation with us! We have cooperated with local Medicine Inspection Center as our QC center. We have customer manufacture sites managed under GMP guidline in Anhui and Jiangsu Province, China. We have good relationship with many pharmaceutical research Institute and Universities in China.
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Q&A
1.How could l get a sample?
Before we received the first order, please afford the sample cost and express fee. We wilreturn the sample cost back to you within your first order.
2.Can you make designs for us?
We have a professional design team to help our customers do design work.Both OEM and ODM orders are accepted.
3.Can we get samples from your factory?
We can provide you samples for free, you just pay express cost.
4.Whether you could make our brand on your products?
Yes. We can print your Logo on both the products and the packages if you can meet our MOQ
How can you provide us high quality products?
5.We have a professional QC team, every product is shipped after strictly examination.
What is your lead time?
Quantity about 10000 pcs is 15-20 days ,small orders are about one week.
Huge orders to be neqotiated.
6.What is your payment?
We accept T/T.L/C.Westem union or to be negotiated.Don't worry about anything, if you have any problems, please feel free to contact us