Our Advantages
1.Free Samples.
2.MOQ:10kg.
3.More than 2000 kinds of animal drugs.
4.More than 11+ manufacturing experience.
5.Certification:MSDS,HALAL,COA,IFRA,ISO9001, ISO22000,26 Allergens, etc.
6.Lead time:about 8-12 working days.
8.Verified by Made-in-China as Golden Supplier.
Product Description
What is Brigatinib / AP26113 Powder ?
It is mainly under investigation for its treatmentefficacy on non-small cell lung cancer (NSCLC) where ALK is activated and EGFP mutations frequently occur.
Pharmaceutical Chemicals Brigatinib Powder CAS 1197953-54-0 Purity Bulk Brigatinib
Product name AP26113
CAS No. 1197958-12-5
Molecular formula C26H34ClN6O2P
Molecular weight 529.01
Purity 99%
Appearance White or almost white powder
Package Aluminum Bag;Drums
Shelf life 2 years
Ap26113;Ap26113 Brigatinib Powder;Brigatinib Ap26113
Function of Apalutamide
Brigatinib, also known as AP-26113, is an orally active, potent and selective Dual ALK/EGFR inhibitor. AP26113 binds to and inhibits ALK kinase and ALK fusion proteins as well as EGFR and mutant forms. This leads to the inhibition of ALK kinase and EGFR kinase, disrupts their signaling pathways and eventually inhibits tumor cell growth in susceptible tumor cells. In addition, AP26113 appears to overcome mutation-based resistance. ALK belongs to the receptor superfamily and plays an important role in nervous system development; ALK dysregulation and gene rearrangements are associated with a series of tumors. EGFR is overexpressed in a variety of cancer cell types.
It induces muscle cells to make more which is a strong myostatin inhibitor. Myostatin (also known as growth differentiation factor 8, is a myokine (protein) produced by muscle cells that acts on muscle cells to inhibit myogenesis. Myogenesis is muscle cell growth and differentiation.
Research through the years show that when you block myostatin, it allows for significantly more muscle mass.
Application
Company Profile
ShangHai Twochem is one of professional groups specialized in research, development, custom manufacturing and trading of pharmaceutical API, advanced intermediates, food supplements, hookah additive flavors ,Cosmetic raw materials, health and cosmetic raw materials, polypeptides, animal drug and organic reagent etc. You can select more than 2000 kinds of raw ingredients here. And we are keeping developing new products and continuously marketing them for sale. You will save lots of time , energy, money and have a very pleasant cooperation with us! We have cooperated with local Medicine Inspection Center as our QC center. We have customer manufacture sites managed under GMP guidline in Anhui and Jiangsu Province, China. We have good relationship with many pharmaceutical research Institute and Universities in China.
Factory display
![Twochem Lab Supply Raw Materials Pharmaceutical Intermediates Brigatinib Powder CAS 1197953-54-0 API with 99% Pruity](//www.micstatic.com/athena/img/transparent.png)
![Twochem Lab Supply Raw Materials Pharmaceutical Intermediates Brigatinib Powder CAS 1197953-54-0 API with 99% Pruity](//www.micstatic.com/athena/img/transparent.png)
Q&A
1.How could l get a sample?
Before we received the first order, please afford the sample cost and express fee. We wilreturn the sample cost back to you within your first order.
2.Can you make designs for us?
We have a professional design team to help our customers do design work.Both OEM and ODM orders are accepted.
3.Can we get samples from your factory?
We can provide you samples for free, you just pay express cost.
4.Whether you could make our brand on your products?
Yes. We can print your Logo on both the products and the packages if you can meet our MOQ
How can you provide us high quality products?
5.We have a professional QC team, every product is shipped after strictly examination.
What is your lead time?
Quantity about 10000 pcs is 15-20 days ,small orders are about one week.
Huge orders to be neqotiated.
6.What is your payment?
We accept T/T.L/C.Westem union or to be negotiated.Don't worry about anything, if you have any problems, please feel free to contact us