Basic Info.
Certification
GMP, Hse, ISO 9001, USP, Bp
Suitable for
Poultry, Pets
Grade Standard
Pharmaceutical Grade
Shelf Life
2 Years Proper Storage
Application
API Raw Materials
Transport Package
Standard Packaging or Customized to Your Needs
Specification
1KG 5KG 25KG 50KG
Product Description
Our Advantages
1.Free Samples.
2.MOQ:10kg.
3.More than 2000 kinds of animal drugs.
4.More than 11+ manufacturing experience.
5.Certification:MSDS,HALAL,COA,IFRA,ISO9001, ISO22000,26 Allergens, etc.
6.Lead time:about 8-12 working days.
8.Verified by Made-in-China as Golden Supplier. Product Description
What is Alpelisib/BYL719 ? Name | Alpelisib,CAS 1217486-61-7 |
Other names | 1217486-61-7 BYL-719 BYL719 Piqray NVP-BYL719 Alpelisib (BYL719) UNII-08W5N2C97Q (S)-N1-(4-Methyl-5-(2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl)thiazol-2-yl)pyrrolidine-1,2-dicarboxamide BYL 719 CHEMBL2396661 08W5N2C97Q (2S)-N1-[4-Methyl-5-[2-(2,2,2-trifluoro-1,1-dimethylethyl)-4-pyridinyl]-2-thiazolyl]-1,2-pyrrolidinedicarboxamide (2S)-1-N-[4-methyl-5-[2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl]-1,3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide 1,2-PYRROLIDINEDICARBOXAMIDE, N1-[4-METHYL-5-[2-(2,2,2-TRIFLUORO-1,1-DIMETHYLETHYL)-4-PYRIDINYL]-2-THIAZOLYL]-, (2S)- C19H22F3N5O2S (2s)-N~1~-{4-Methyl-5-[2-(1,1,1-Trifluoro-2-Methylpropan-2-Yl)pyridin-4-Yl]-1,3-Thiazol-2-Yl}pyrrolidine-1,2-Dicarboxamide (S)-N1-(4-methyl-5-(2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl)thiazol-2-yl)pyrrolidine-1,2-dicarboxamide. |
Key words | STUWGJZDJHPWGZ-LBPRGKRZSA-N; API; Alpelisib uses |
CAS number | 1217486-61-7 |
Molecular Formula | C19H22F3N5O2S |
Molecular Weight | 441.47g/mol |
Chemical and Physical Properties |
Appearance | White powder |
Melting point | N/A |
Solubility | Soluble in DMSO |
Quality standard | 98% |
Application |
Drug Indication/Application/Use | Anti-tumor |
Formulations/Preparations | Tablets |
Handling and Storage |
Safety and Hazards | The shanghai Research Institute of Chemical industry testing center identification conclusion :1 None hazard identification, 2 The substance is not subject to IATA DGR, 3 Non packing requirements. |
Handling and Storage | Under inert gas (nitrogen or Argen) at 2-8°C |
Sample package | Double plastic bags inside, aluminum foil bag outside |
Commercial package | Double plastic bags inside,5kg, 10kg, 25kg fiber drum outside. |
UN Code | Not classified |
HS Code | 000000000 |
Shipping group | Shipment at ambient temperature for no controlled and no dangerous goods |
Sales restriction | No |
Origin | China |
Technnical support |
Alpelisib,STD Data sheet Alpelisib,MSDS Alpelisib,COA Alpelisib,Transport Certificate | Yes Yes Yes Yes |
Related APIs | (2S,3S)-1-N-[5-(2-tert-butyl-1,3-thiazol-4-yl)-4-methyl-1,3-thiazol-2-yl]-3-methylpyrrolidine- 1,2-dicarboxamide; (S)-N1-(2-(tert-butyl)-4'-methyl-[4,5'-bithiazol]-2'-yl)pyrrolidine-1,2-dicarboxamide; (2S)-2-methyl-1-N-[4-methyl-5-[2-(1-methylcyclopropyl)pyridin-4-yl]-1,3-thiazol-2-yl]pyrrolidine-1,2- dicarboxamide; (2S)-1-N-[5-(2-cyclopropylpyridin-4-yl)-4-methyl-1,3-thiazol-2-yl]-2-methylpyrrolidine-1,2-dicarboxamide; (2S)-1-N-[5-(2-cyclobutylpyridin-4-yl)-4-methyl-1,3-thiazol-2-yl]-2-methylpyrrolidine-1,2-dicarboxamide; (2S)-1-N-[5-[2-(2-fluorophenyl)pyridin-4-yl]-4-methyl-1,3-thiazol-2-yl]-2-methylpyrrolidine-1,2-dicarboxamide |
Supply ability |
Monthly capacity | / |
GMP | No |
Function of ApalutamideAlpelisib is used for advanced solid tumours. Alpelisib shows statistically significant dose-dependent anti-tumor efficacy in PIK3CA mutant xenograft models in rodents. BYL719 has a low clearance, a half-life of 8.5 h and its exposure increases dose proportionally between 30mg/d and 450mg/d, displaying a low inter-individual variability in Cmax and AUC in human. BYL719(270mg/d) shows first signs of clinical efficacy include 1 confirmed partial response in a patient with ER+ breast cancer, and significant PET responses (PMR) and/or tumor shrinkage are achieved in 8 out of 17 evaluated patients.
Application
Company Profile
ShangHai Twochem is one of professional groups specialized in research, development, custom manufacturing and trading of pharmaceutical API, advanced intermediates, food supplements, hookah additive flavors ,Cosmetic raw materials, health and cosmetic raw materials, polypeptides, animal drug and organic reagent etc. You can select more than 2000 kinds of raw ingredients here. And we are keeping developing new products and continuously marketing them for sale. You will save lots of time , energy, money and have a very pleasant cooperation with us! We have cooperated with local Medicine Inspection Center as our QC center. We have customer manufacture sites managed under GMP guidline in Anhui and Jiangsu Province, China. We have good relationship with many pharmaceutical research Institute and Universities in China. Factory display
Q&A
1.How could l get a sample?
Before we received the first order, please afford the sample cost and express fee. We wilreturn the sample cost back to you within your first order.
2.Can you make designs for us?
We have a professional design team to help our customers do design work.Both OEM and ODM orders are accepted.
3.Can we get samples from your factory?
We can provide you samples for free, you just pay express cost.
4.Whether you could make our brand on your products?
Yes. We can print your Logo on both the products and the packages if you can meet our MOQ
How can you provide us high quality products?
5.We have a professional QC team, every product is shipped after strictly examination.
What is your lead time?
Quantity about 10000 pcs is 15-20 days ,small orders are about one week.
Huge orders to be neqotiated.
6.What is your payment?
We accept T/T.L/C.Westem union or to be negotiated.Don't worry about anything, if you have any problems, please feel free to contact us
Address:
N/a, Shanghai, China
Business Type:
Trading Company
Business Range:
Chemicals
Management System Certification:
ISO 9001, OHSAS/ OHSMS 18001, HSE, ISO 14064, QC 080000, GMP, BSCI, IFS, PAS 28000
Company Introduction:
Shanghai Twochem is one of professional groups specialized in research, development, custom manufacturing and trading of pharmaceutical API, advanced intermediates, food supplements/Cosmetic raw materials, health and cosmetic rawmaterials, herbal extracts, polypeptides and prostaglandin derivatives etc.